Evaluation of a standardized protocol for thrombin generation using the calibrated automated thrombogram: A Nordic study
نویسندگان
چکیده
منابع مشابه
Whole-blood thrombin generation monitored with a calibrated automated thrombogram-based assay.
BACKGROUND The calibrated automated thrombogram (CAT) assay in plasma is a versatile tool to investigate patients with hypo- or hypercoagulable phenotypes. The objective was to make this method applicable for whole blood measurements. METHODS Thin-layer technology and the use of a rhodamine 110-based thrombin substrate appear to be essential for a reliable thrombin generation (TG) assay in wh...
متن کاملThrombin generation increasing with age and decreasing with use of heparin indicated by calibrated automated thrombogram conducted in Chinese.
OBJECTIVE Calibrated Automated Thrombogram(CAT) is a test to monitor the generation of thrombin. It can be described by four parameters: lag time, peak thrombin, endogenous thrombin potential (ETP) and time to peak (ttPeak). This study aims to determine the normal ranges of CAT parameters in Chinese, and evaluate whether thrombin generation is correlated with the concentration of heparin/low mo...
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ژورنال
عنوان ژورنال: Haemophilia
سال: 2019
ISSN: 1351-8216,1365-2516
DOI: 10.1111/hae.13640